Organization of DNA in chromosomes

At the end of this activity, students should be able to:
– present the levels of DNA organization from double helix to metaphase chromosome
– explain the role of histones in the spatial structure of DNA
– present the morphology of metaphase chromosome
– define homologous chromosomes, autosomes and heterosomes
– describe a karyotype and the principles of its preparation
– explain the terms locus, allele, homozygote and heterozygote.